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Giant canisters of frozen bull semen caused a scare near Nashville when they fell off a Greyhound bus and began smoking on the road, officials said.

Emergency crews shut down a stretch of Interstate 65 just south of downtown Nashville at around 6 a.m. Tuesday after panicked motorists reported seeing the steaming canisters and smelling a foul odor.

Officials traced the canisters to a Greyhound bus, whose driver wasn't aware that he'd lost his load, WKRN television reported.

The cattle sperm, which was packed in liquid nitrogen and worth as much as $80,000, was traveling from Columbus, Ohio, to a breeding farm in Laredo, Texas, the station said.